To identify the safety of seed coating with neonicotinoids for maize and its effect on main pests,the effects of recommended middle dose,and its 1. 5 times and 2 times doses of 600 g / L imidacloprid FS,70% imidacloprid WS and 30% thiamethoxam FS on maize emergence,growth,yields and main pests were studied. The results showed that they were safe to maize emergence and the germination rate increased by 6. 04% —11. 25%. At 20 days after sowing,70% imidacloprid WS and 30% thiamethoxam FS promoted the growth of maize,with increase of plant height,secondary root number and fresh( dry)weights,and 600 g / L imidacloprid FS promoted root growth but slightly inhibited the aboveground growth.The increasing root-top ratio and better seedling shape were obtained in all treatments. Seed treatments al-leviated the damages of underground pests and aphids,but the damage of Asia corn borer had a serious trend. The yield indicators in all treatments were better than or equivalent to the control,but there were no significant differences among doses. The yield increase ranged from 2. 46% to 20. 48% in treatments,with increase of 19. 04%,20. 41% and 20. 48% in treatment of 600 g / L imidacloprid FS at 1. 5 times doses,70% imidacloprid WS at 2 times doses and 30% thiamethoxam FS at 2 times doses,respectively. These results indicate that seed coating with imidacloprid and thiamethoxam agents is safe for maize growth,but the prevention and control of non-target pests in seed treatment field should be paid more attention in order to obtain better harvest.