Objective:To construct animal models of articular cartilage lesions in the knee of goats by arthroscopy to minimize the surgical injury.Methods:Subchondral drilling to create the chondral defect on articular cartilage were performed on 9 goats(9 joints) by arthroscope.Results:The chondral defect models were successefully constructed on 9 goats(9 joints)and accurately located by arthroscopy.Conclusion:Preparing animal models of chondral defects by arthroscopy result in fewer injuries and experimental errors as compared with open surgery.