The Lattice flow diverter for the treatment of intracranial aneurysms: a single center experience in 117 consecutive aneurysms

BACKGROUND: Flow diversion has revolutionized the management of intracranial aneurysms. This study aimed to evaluate the preliminary safety and efficacy profile of the novel Lattice flow diverter (LFD) in clinical applications. METHODS: We retrospectively analyzed consecutive patients with intracranial aneurysms who were treated with the LFD between June 2023 and May 2024. Based on the medical records and imaging data, we collected demographic characteristics, aneurysm features, procedural details, perioperative complications, clinical outcomes, and imaging results. RESULTS: This study comprised 105 patients (mean age, 55.4±9.04 years; 72.4% female) with 117 aneurysms, including 104 (88.9%) anterior circulation aneurysms. Procedural success was achieved in all patients (109 devices deployed). Adjunctive techniques included coiling in 39 aneurysms (33.3%) and balloon-assisted wall apposition in three cases (2.6%). The overall perioperative complication rate was 5.8%, with neurological complications (all ischemic events) occurring in 2.9% of cases. Clinical follow-up (mean 10.0±1.4 months) demonstrated preserved functional independence (modified Rankin Scale (mRS) score 0-2) in 98.0% of patients. Imaging follow-up (mean 6.6±1.6 months) revealed complete occlusion in 71.9% of aneurysms and adequate occlusion (Raymond-Roy class I/II) in 88.6%. CONCLUSION: The LFD demonstrated favorable safety and efficacy characteristics for intracranial aneurysm treatment during short-term follow-up. Long-term outcomes require validation in multicenter prospective cohort studies.