纳米技术
纳米颗粒
姜黄素
封装(网络)
成分
药物输送
材料科学
纳米-
化学
计算机科学
计算机网络
生物化学
食品科学
复合材料
作者
Xiaojia Yan,Moting Li,Xingfeng Xu,Xuebo Liu,Fuguo Liu
标识
DOI:10.3389/fnut.2022.999373
摘要
Zein is a kind of excellent carrier materials to construct nano-sized delivery systems for hydrophobic bioactives, owing to its unique interfacial behavior, such as self-assembly and packing into nanoparticles. In this article, the chemical basis and preparation methods of zein nanoparticles are firstly reviewed, including chemical crosslinking, emulsification/solvent evaporation, antisolvent, pH-driven method, etc., as well as the pros and cons of different preparation methods. Various strategies to improve their physicochemical properties are then summarized. Lastly, the encapsulation and protection effects of zein-based nano-sized delivery systems (e.g., nanoparticles, nanofibers, nanomicelles and nanogels) are discussed, using curcumin as a model bioactive ingredient. This review will provide guidance for the in-depth development of hydrophobic bioactives formulations and improve the application value of zein in the food industry.
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