医学
分流器
动脉瘤
闭塞
外科
不利影响
抗血栓
血栓形成
血管成形术
神经血管束
支架
气球
回顾性队列研究
放射科
内科学
作者
Dominik F Vollherbst,Hannes Luecking,J. DuPlessis,M. Sonnberger,Christoph J. Maurer,Naci Koçer,Monika Killer‐Oberpfalzer,Riitta Rautio,Luca Valvassori,Ansgar Berlis,S. Gasser,Simon Gatt,A. Dörfler,Martin Bendszus,Markus Möhlenbruch
出处
期刊:American Journal of Neuroradiology
[American Society of Neuroradiology]
日期:2023-03-30
卷期号:44 (4): 474-480
被引量:7
摘要
Flow diverters with antithrombotic coatings are increasingly used to improve the safety of flow diverter treatments of intracranial aneurysms. This study aimed to investigate the safety and short-term efficacy of the new FRED X flow diverter.Medical charts and procedural and imaging data of a consecutive series of patients with intracranial aneurysms who were treated with the FRED X at 9 international neurovascular centers were retrospectively analyzed.One hundred sixty-one patients (77.6% women; mean age, 55 years) with 184 aneurysms (11.2% acutely ruptured) were included in this study. Most aneurysms were located in the anterior circulation (77.0%), most frequently at the ICA (72.7%). The FRED X was successfully implanted in all procedures. Additional coiling was performed in 29.8%. In-stent balloon angioplasty was necessary in 2.5%. The rate of major adverse events was 3.1%. Thrombotic events occurred in 7 patients (4.3%) with 4 intra- and 4 postprocedural in-stent thromboses, respectively (1 patient had both peri- and postprocedural thrombosis). Of these thrombotic events, only 2 (1.2%) led to major adverse events (ischemic strokes). Postinterventional neurologic morbidity and mortality were observed in 1.9% and 1.2%, respectively. The rate of complete aneurysm occlusion after a mean follow-up of 7.0 months was 66.0%.The new FRED X is a safe and feasible device for aneurysm treatment. In this retrospective multicenter study, the rate of thrombotic complications was low, and the short-term occlusion rates are satisfactory.
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