三环
克拉斯
医学
计算生物学
癌症
生物信息学
药理学
内科学
结直肠癌
生物
作者
Tao-Qian Zhao,Steven H. Liang
标识
DOI：10.1021/acsmedchemlett.4c00609
摘要
The invention described in this patent application relates to oral compounds represented by Formula I. These compounds are designed to specifically target and inhibit KRAS alleles, providing both therapeutic and prophylactic potential in mammals, particularly for the treatment of KRAS-driven cancers.
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