Mechanically Regulating Cardiac Preload to Maximize Left Ventricular Unloading With a Transvalvular Microaxial Flow Pump

HomeCirculation: Heart FailureVol. 17, No. 4Mechanically Regulating Cardiac Preload to Maximize Left Ventricular Unloading With a Transvalvular Microaxial Flow Pump No AccessLetterRequest AccessFull TextAboutView Full TextView PDFView EPUBSections ToolsAdd to favoritesDownload citationsTrack citationsPermissions ShareShare onFacebookTwitterLinked InMendeleyReddit Jump toNo AccessLetterRequest AccessFull TextMechanically Regulating Cardiac Preload to Maximize Left Ventricular Unloading With a Transvalvular Microaxial Flow Pump Navin K. Kapur, Lara Reyelt, Kay Everett, Elena Mahmoudi, Madison S. Kapur, Jacob S. Ellis, Lija Swain, Xiaoying Qiao, Shreyas Bhave and Genya Sunagawa Navin K. KapurNavin K. Kapur Correspondence to: Navin K. Kapur, MD, 800 Washington St, Box No. 80, Boston, MA 02111. Email E-mail Address: [email protected] The Molecular Cardiology Research Institute, Tufts Medical Center, Boston, MA. , Lara ReyeltLara Reyelt https://orcid.org/0000-0001-6242-5926 The Molecular Cardiology Research Institute, Tufts Medical Center, Boston, MA. , Kay EverettKay Everett https://orcid.org/0000-0002-5949-0812 The Molecular Cardiology Research Institute, Tufts Medical Center, Boston, MA. , Elena MahmoudiElena Mahmoudi The Molecular Cardiology Research Institute, Tufts Medical Center, Boston, MA. , Madison S. KapurMadison S. Kapur The Molecular Cardiology Research Institute, Tufts Medical Center, Boston, MA. , Jacob S. EllisJacob S. Ellis https://orcid.org/0009-0000-3450-2728 The Molecular Cardiology Research Institute, Tufts Medical Center, Boston, MA. , Lija SwainLija Swain https://orcid.org/0000-0001-7713-606X The Molecular Cardiology Research Institute, Tufts Medical Center, Boston, MA. , Xiaoying QiaoXiaoying Qiao The Molecular Cardiology Research Institute, Tufts Medical Center, Boston, MA. , Shreyas BhaveShreyas Bhave https://orcid.org/0000-0003-0393-0978 The Molecular Cardiology Research Institute, Tufts Medical Center, Boston, MA. and Genya SunagawaGenya Sunagawa The Molecular Cardiology Research Institute, Tufts Medical Center, Boston, MA. Originally published1 Mar 2024https://doi.org/10.1161/CIRCHEARTFAILURE.123.011330Circulation: Heart Failure. 2024;17FootnotesFor Sources of Funding and Disclosures, see page 377.Correspondence to: Navin K. Kapur, MD, 800 Washington St, Box No. 80, Boston, MA 02111. Email nkapur@tuftsmedicalcenter.orgREFERENCES1. Fukamachi K, Shiose A, Massiello A, Horvath DJ, Golding LA, Lee S, Starling RC. Preload sensitivity in cardiac assist devices.Ann Thorac Surg. 2013; 95:373–380. doi: 10.1016/j.athoracsur.2012.07.077CrossrefMedlineGoogle Scholar2. Saku K, Kakino T, Arimura T, Sunagawa G, Nishikawa T, Sakamoto T, Kishi T, Tsutsui H, Sunagawa K. Left ventricular mechanical unloading by total support of impella in myocardial infarction reduces infarct size, preserves left ventricular function, and prevents subsequent heart failure in dogs.Circ Heart Fail. 2018; 11:e004397. doi: 10.1161/CIRCHEARTFAILURE.117.004397LinkGoogle Scholar3. Swain L, Reyelt L, Bhave S, Qiao X, Thomas CJ, Zweck E, Crowley P, Boggins C, Esposito M, Chin M, et al. Transvalvular ventricular unloading before reperfusion in acute myocardial infarction.J Am Coll Cardiol. 2020; 76:684–699. doi: 10.1016/j.jacc.2020.06.031CrossrefMedlineGoogle Scholar4. Kapur NK, Kiernan MS, Gorgoshvili I, Yousefzai R, Vorovich EE, Tedford RJ, Sauer AJ, Abraham J, Resor CD, Kimmelstiel CD, et al. Intermittent occlusion of the superior vena cava to improve hemodynamics in patients with acutely decompensated heart failure: the VENUS-HF early feasibility study.Circ Heart Fail. 2022; 15:e008934. doi: 10.1161/CIRCHEARTFAILURE.121.008934LinkGoogle Scholar5. Kapur NK, Jumean M, Halin N, Kiernan MS, DeNofrio D, Pham DT. Ventricular square-wave response: case illustrating the role of invasive hemodynamics in the management of continuous-flow left ventricular assist device dysfunction.Circ Heart Fail. 2015; 8:652–654. doi: 10.1161/CIRCHEARTFAILURE.115.002160LinkGoogle Scholar Previous Back to top Next FiguresReferencesRelatedDetails April 2024Vol 17, Issue 4 Advertisement Article InformationMetrics © 2024 American Heart Association, Inc.https://doi.org/10.1161/CIRCHEARTFAILURE.123.011330PMID: 38626066 Originally publishedMarch 1, 2024 Keywordsanimalarteriescatheterhemodynamicsoxygen consumptionPDF download Advertisement SubjectsAnimal Models of Human DiseaseCatheter-Based Coronary and Valvular InterventionsHeart Failure