Determination of Three Kinds of Bisphenols in Soak Water of Plastic Materials for Drinking Water Supply System by Solid Phase Extraction-Liquid Chromatography-Tandem Mass Spectrometry

Objective To develop a method for the determination of bisphenol F,bisphenol A and tetrabromobisphenol A in soak water of the materials for drinking water supply system.Methods A total of 30 materials for drinking water supply system were leached at room temperature for(24±1) hours.200 ml soak water were preconcentrated on C18 solid phase extraction cartridge,and bisphenol F,bisphenol A and tetrabromobisphenol A were quantitatively analyzed by liquid chromatography tandem mass spectrometry(LC-MS-MS)method.Results The calibration curves of bisphenol F,bisphenol A and tetrabromobisphenol A showed a good linearity in the range of 0.027-333,0.032-333 and 0.006-333 μg/L respectively,and the correlation coefficients were more than 0.999.The limits of quantification(LOQ)of bisphenol F,bisphenol A and tetrabromobisphenol A were 27,32 and 6 ng/L respectively.The spiked recoveries ranged from 77.4% to 117.0% with the relative standard deviations of 3.9%-17.0%.Conclusion The method is sensitive,accurate,and applicable to the determination of bisphenol F,bisphenol A and tetrabromobisphenol A in soak water of the materials for drinking water supply system.