医学
保持生育能力
卵巢早衰
生育率
特纳综合征
妇科
年轻人
卵巢储备
卵巢癌
癌症
儿科
内科学
不育
怀孕
人口
环境卫生
生物
遗传学
作者
Nicole Ulrich,Nicholas Raja,Erin Ellman,Molly B. Moravek
出处
期刊:Journal of adolescent and young adult oncology
[Mary Ann Liebert]
日期:2022-08-01
卷期号:11 (4): 427-432
被引量:2
标识
DOI:10.1089/jayao.2021.0115
摘要
Adolescents and young adults (AYAs) at risk of primary ovarian insufficiency (POI) often request fertility preservation consultation. We report consult/treatment outcomes for 21 cancer survivors and 3 mosaic Turner syndrome (TS) patients (mean age 21.6 at consult, 3 with POI). Ten AYAs (9 survivors, 1 mosaic TS) attempted ovarian stimulation; 4 cancelled for poor response. Of completed cycles, mean 3.8 mature oocytes were retrieved, with mean anti-Müllerian hormone 0.653 ng/mL. Ovarian stimulation for mosaic TS AYA and survivors is possible, even with diminished ovarian reserve. Further study is needed to establish guidelines for patient selection, treatment timing, and stimulation protocols.
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