[Clinical practice consensus on dietary interventions for autism spectrum disorder (2025 edition)].

医学 干预(咨询) 自闭症谱系障碍 心理干预 自闭症 限制 临床实习 梅德林 神经发育障碍 发育障碍 重症监护医学 精神科 临床心理学 医学营养疗法 系统回顾 临床试验 应用行为分析 卫生专业人员 儿科 饮食管理 功能(生物学) 医疗保健
出处
期刊:PubMed [National Institutes of Health]
卷期号:65 (4): 314-325
标识
DOI:10.3760/cma.j.cn112138-20250929-00584
摘要

Autism spectrum disorder (ASD) is a severe neurodevelopmental condition among children in China, with a prevalence of approximately 1.8%. In addition to core features-including deficits in language and communication, stereotyped behaviors, and restricted interests-many patients present with dietary imbalance, nutritional deficiencies, gastrointestinal symptoms, and gut dysbiosis. Dietary patterns influence neurodevelopment and nervous system function through the gut-brain axis. Over recent years, dietary interventions have been increasingly incorporated into comprehensive ASD management and have demonstrated benefits in alleviating gastrointestinal disturbances and specific ASD-related symptoms. However, given the high heterogeneity of ASD, treatment responses vary considerably, and no standardized or widely accepted intervention strategy has been established. Based on available scientific evidence and clinical practice, this consensus proposes a framework and provides recommendations for dietary intervention in ASD. The core recommendations include recognizing dietary intervention as a fundamental component of ASD treatment; advocating for a balanced and healthy diet while limiting high-sugar and ultra-processed foods; and implementing specific dietary approaches in combination with individualized nutritional supplementation according to coexisting multisystem symptoms. The aim of this consensus was to provide clinical guidance for healthcare professionals, promote the application of dietary interventions, and improve clinical outcomes and prognosis for individuals with ASD.
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