辅活化剂
TAF4
一般转录因子
生物
RNA聚合酶Ⅱ
塔夫2
分子生物学
GATAD2B型
抄写(语言学)
转录因子ⅡD
激活剂(遗传学)
转录因子
RNA聚合酶Ⅱ全酶
细胞生物学
基因
发起人
生物化学
基因表达
抑制因子
哲学
语言学
作者
N. Lynn Henry,David Bushnell,Roger D. Kornberg
标识
DOI:10.1074/jbc.271.36.21842
摘要
A yeast protein has been identified that stimulates basal transcription by RNA polymerase II, binds both single- and double-stranded DNA, and interacts with both a general transcription factor and a transcriptional activator. Phosphorylation appears to regulate these interactions. The gene for the transcriptional stimulatory protein, termed TSP1, was cloned and found to be dispensable for yeast cell viability. The deduced amino acid sequence is similar to that of mammalian coactivator protein PC4.
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