癌症研究
生物
转移
前列腺癌
激酶
PTEN公司
转移抑制因子
癌症
细胞生物学
PI3K/AKT/mTOR通路
信号转导
遗传学
作者
Aditya Ganju,Subhash C. Chauhan,Bilal Bin Hafeez,Kyle Doxtater,Manish K. Tripathi,Nadeem Zafar,Murali M. Yallapu,Rakesh Kumar,Meena Jaggi
摘要
Overall, this study, for the first time, establishes that PKD1 is an upstream regulatory kinase of MTA1 status and its associated metastatic activity, and that the PKD1-MTA1 axis could be targeted for anti-cancer strategies.
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