Measurement and Correlation of Solubilities of Luteolin in Organic Solvents at Different Temperatures

The solubilities of luteolin in methanol, ethanol, 1-propanol, 2-propanol, 1-butanol, acetone, hexane, and dimethyl sulfoxide (DMSO) at T = (273.15, 283.15, 298.15, 313.15, and 333.15) K were measured. The solubility of luteolin increases with increasing temperature, but there was no correlation with the number of carbon in the solvents. The nonideal solution model and an empirical equation were used to correlate the solid−liquid equilibrium data.