Chronic kidney disease(CKD)is a common and frequently-occuring disease,and it is also an important disease which seriously endangers human health.The rule of treating the undiseased in Internal Medicine includes prevention before disease occurring,stopping the disease's occurrence;prevention of contagion when disease has existed;defencing the disease after recovery.To sum up,it is the prevention of the occurrence and development of diseases.That is before the disease to prevent the occurrence of disease,after the disease to prevent the contagion of disease,alleviation of disease to prevent the recurrence of disease.This paper tries to use the theory of treating the undiseased in Internal Medicine to the prevent and treat CKD from the aspects of prevention before disease occurring,stopping the disease's occurrence;prevention of contagion when disease has existed,defencing the disease after recovery.