Study on the Inhibitory Effects of Natural Sweetner Mogrosides on Radical and Lipid Peroxidation

【Objective】The antioxidant activity of mogroside extract (MG) and mogroside V in vitro was studied.【Method】D-deoxyribose method, reagent box method and spectrophotometry method were used to determine the inhibitory effect on radical, hemolysis of red blood cells and lipid peroxidation【.Result】(1) It was found that mogroside extract could scavenge different radicals effectively, protect liver tissue in rat from peroxidation induced by Fe2+ or H2O2 and inhibit the hemolysis of red blood cells. (2) The scavenging .OH effect of mogroside V was the same as mogroside extract, but its scavenging O2-. effect was better than that of MG.【Conclusion】It is concluded that mogroside extract has antioxidant effects and mogroside V may be the main antioxidant components of the extract.