Prophylactic Effect of Sodium Modeling Hemodialysis on Dialysis Hypotension in High Risk Patients

Objective:To assess the prophylactic effect of sodium modeling hemodialysis on hypotension during hemodialysis in patients with high risk factors(elderly,diabetic nephropathy and cardiac insufficiency).Methods:30regular hemodialysis patients with above risk factors was employed,Under the conditions of same blood flow and constantul trafiltration volume,all patients were performed conventional hemodialysis(CHD) at the first month wth the sodium concertation of Hemodialysis fluid 138mmol/L(A group) and sodium profile hemodialysis(PHD) at the second month with the sodium concertation of Hemodialysis fluid reduced from 148 mmol/L to 135mmol/L(B group),the serum concertations of sodium were detected pre-Hemodialysis and post-Hemodialysis,respectively,the occurrence of hypotension during Hemodialysis was also observed during Hemodialysis.Results:(1)compared with group B,no obvious difference of serum sodium concertation occurred between pre Hemodialysis and post-Hemodialysis in group A(P0.05),(2)the occurrence rate of hypotension in group B was significantly reduced compared with group A(P0.01),(3) compared with group A,PHD plays its therapeutic role without the increase of sodium burden and body weight.Conclusion:sodium modeling hemodialysis can obviously prevent the occurrence of dialysis hypotension in patients with high risk factors.