医学
阿法替尼
相伴的
表皮生长因子受体
肺癌
外显子
腺癌
肿瘤科
内科学
突变
克里唑蒂尼
癌症研究
埃罗替尼
癌症
基因
遗传学
生物
恶性胸腔积液
作者
Diego Kauffmann-Guerrero,Kathrin Kahnert,Jörg Kumbrink,Zulfiya Syunyaeva,Amanda Tufman,Rudolf M. Huber
标识
DOI:10.1016/j.cllc.2018.09.009
摘要
A 53-year old white, female former-smoker (15 pack-years) was diagnosed with non–small-cell lung cancer (NSCLC) of the middle lobe in April 2016. Histopathologic evaluation revealed an adenocarcinoma with a common sensitizing (Exon 19 deletion) epidermal growth factor receptor (EGFR) mutation (c.2235_2249delGGAATTAAGAGAAGC, p.Glu746_Ala750del). The initial tumor stage was cT2 cN3 cM0. The patient presented herself in good general condition (performance status [PS], 0) and with a history of Hashimoto thyroiditis and no further comorbidity.
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