化学
串联
弗里德尔-克拉夫茨反应
烷基化
分子间力
催化作用
酚类
有机化学
级联反应
氢
分子
复合材料
材料科学
作者
Yan‐Chao Wu,Li Liu,Yuliang Liu,Dong Wang,Yongjun Chen
摘要
The tandem reaction of phenols and chalcones in refluxing TFA gave the flavylium species of 2-hydroxy-2-phenyl-2H-chromenes in moderate to good isolated yields. The reaction was proposed to involve a tandem transformation of Friedel−Crafts alkylation, dehydrative cyclization, intermolecular hydrogen transfer, and hydration. As a multifunctional catalyst, TFA mediated the processes efficiently and cleanly.
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