[Viewpoint of systematic lymphadenectomy for intrahepatic cholangiocarcinoma patients].

医学 肝内胆管癌 淋巴结切除术 淋巴结 淋巴 放射科 转移 解剖(医学) 外科 癌症 病理 内科学
作者
Weiwei Lu,Zhao-you Tang,Zhiwei Quan
出处
期刊:PubMed 卷期号:57 (4): 247-252 被引量:2
标识
DOI:10.3760/cma.j.issn.0529-5815.2019.04.002
摘要

Intrahepatic cholangiocarcinoma(ICC) is the second common primary liver cancer originated from epithelium of the sub-branches of intrahepatic bile ducts with extremely poor prognosis and lack of effective treatment.The prognosis of ICC is mostly affected by the origin,the type and the size of the tumor as well as the intrahepatic metastasis(satellite lesion) and lymph node metastasis etc.Surgical resection remains the first choice of treatment to patients with ICC.However, there are multiple issues in surgical treatment of ICC, which have not been reached a consensus.Among them, the value of systematic lymphadenectomy during hepatic resection for ICC patient remains one of the hot spot issues.Given the heterogeneity of ICC,we recommend planning the procedure of the radical resection and lymphadenectomy personally, according to the type and origin of the tumor, the number and locationof the lesion.The pre-operation imaging examination and the intra-operation lymph node tracing technique could provide valuable information to help the surgeon decide the range of systematic lymphadenectomy.Routine systematic lymphadenectomy is recommended in the surgical treatment of ICC patients by experienced surgeons even without evidence of lymph node metastasis.The resected lymph tissue should be labeled by the provenance for further study.肝内胆管癌(ICC)恶性程度高,预后与肿瘤类型、大小、数目、分期及淋巴结转移等密切相关,根治性手术是患者获得治愈的唯一方法,但ICC的外科治疗尚有较多问题未达成共识,其中是否常规淋巴结清扫及清扫范围的确定是争议热点。建议根据肿瘤性质和大小、肝内肿瘤数目、范围等规划手术方式及确定是否需联合淋巴结清扫等。不同部位ICC的淋巴结转移途径存在差异,淋巴结清扫范围也应相应调整。术前影像学检查及术中淋巴结示踪技术对决定淋巴结清扫范围有一定帮助。鉴于ICC的异质性特征,对于术前未发现淋巴结转移的ICC,为了精确分期,建议有条件的单位常规开展淋巴结清扫术,并标记部位。.
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