肿瘤缺氧
光动力疗法
前药
活性氧
氧气
药理学
缺氧(环境)
吉西他滨
癌症研究
免疫原性细胞死亡
化学
肿瘤微环境
癌细胞
癌症
医学
放射治疗
内科学
生物化学
肿瘤细胞
有机化学
作者
Zhiwan Wang,Xiang Gong,Jie Li,Hong Wang,Xiaoxuan Xu,Yaping Li,Xianyi Sha,Zhiwen Zhang
出处
期刊:ACS Nano
[American Chemical Society]
日期:2021-02-24
卷期号:15 (3): 5405-5419
被引量:100
标识
DOI:10.1021/acsnano.1c00033
摘要
DG+L) significantly retarded the tumor growth with an 82.96% inhibition in the 4T1 breast cancer model and a 93.6% inhibition in the PANC02 pancreatic cancer model with better therapeutic benefits than non-oxygen-delivering nanovehicles. Therefore, this study presents an encouraging polyfluorocarbon nanovehicle with deep tumor-penetrating and hypoxia-relieving capacity to boost antitumor immunity for cancer treatment.
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