Causes and countermeasures of pancreatic fistula after pancreaticoduodenectomy

Objective To discuss the experiences in the prevention and treatment of pancreatic fistula after pancreaticoduodenectomy. Methods We retrospectively analyzed 209 cases received pancreaticoduodenectomy from 1995 to 2010. We analyzed the causes of pancreatic fistula, prevention and treatment of pancreatic fistula. Results Incidence of pancreatic fistula had no significant difference betweenthe different age, gender, pancreatic texture, with or without preoperative jaundice, anemia, hypoproteinemia and different surgical approach of pancreatojejunostomy. Incidence of pancreatic fistula had significant difference between different surgical groups (surgical techniques). Conclusions Appropriate perioperative management, skilled surgical operation can significantly reduce the incidence of pancreatic fistula. Skilled surgical operation, particularly pancreatic and intestinal anastomosis individualized treatment is crucial to prevent pancreatic fistula after PD. Key words: Pancreaticoduodenectomy ;  Pancreatic fistula ;  Treatment ;  Prevention ;