AB0630 CLINICAL CHARACTERISTICS ANALYSIS AND LITERATURE REVIEW OF 55 CASES OF PANNICULITIS

Background:

Panniculitis is a heterogeneous inflammatory disease involving subcutaneous fat. It can be divided into different subtypes according to the clinical characteristics and pathological changes of the disease. Because the cause of panniculitis is unclear, clinical manifestations are diverse, lack of specificity, early diagnosis is difficult, and misdiagnosis and missed diagnosis are prone to occur.

Objectives:

To improve the clinical understanding of the disease by retrospective analysis of 55 cases of patients with panniculitis.

Methods:

The hospitalized patients with panniculitis were collected from December2011 to October 2018 in the Shanxi Dayi Hospital affiliated to Shanxi Medical University. The demographics, clinical manifestations, auxiliary examinations and treatments were analyzed and summarized.

Results:

The proportion of males and females in the 55 patients was 1:2.23, with an average of 53.3 years (18-82 years). A total of 52 cases of nodular panniculitis (including 14 cases of mesenteric involvement) and 3 cases of special type of panniculitis were collected. Patients with nodular panniculitis often find subcutaneous nodules or masses. According to the affected parts, they are divided into skin type and system type. Among them, 10 cases are skin type and 42 cases are system type. The most common parts is mesenteric and kidney involvement. 9 of 55 patients was combined with tumor. Patients with mesenteric panniculitis mainly present abdominal pain and bloating, which are mainly diagnosed according to CT. Patients with systemic panniculitis can be significantly relieved after treatment with hormones and immunosuppressive agents.

Conclusion:

Panniculitis is an inflammatory disease of unknown etiology. It is common in middle-aged and elderly people. It has various clinical manifestations and lacks specificity. The diagnosis is mainly based on pathological results. It is easy to be combined with tumors. When subcutaneous nodules are found, pathological examination should be improved in time in order to avoid misdiagnosis.

References

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Disclosure of interests:

None declared