Synthetic method and characterization of novel phthalamide derivatives

The aim of present scheme is to synthesize of new phthalamide heterocycles and elucidates their biological activity. For the synthesis, phthalamide molecule was treated with various reagents as per the requirement of reaction and every time it result in to the formation of novel derivative of phthalamide. Derivatives obtained were bromo, benzimidazol, isothiocyanate, acetyl, benzothiazol, isothiocyanate and diazepin. Obtained derivatives further studied for their characterization using spectral techniques like IR, NMR and elemental analysis which established the structure of derivative. Derivatives tested for their antibacterial activity against gram positive and gram negative bacterial strains like E. coli and S. aureus.