医学
射频消融术
转移
存活率
随机对照试验
胃肠病学
内科学
总体生存率
烧蚀
肝细胞癌
肝切除术
外科
切除术
癌症
作者
Won Suk Lee,Seong Hyeon Yun,Ho-Kyung Chun,Woo Yong Lee,Jong Man Kim,Seong-Ho Choi,Jin-Seok Heo,Jae‐Won Joh,Dongil Choi,Seung‐Hoon Kim,Hyunchul Rhim,Hyung Bin Lim
标识
DOI:10.1097/mcg.0b013e318064e752
摘要
Background The role of the radiofrequency ablation (RFA) in treatment of solitary liver metastasis has not been established yet. Both hepatic resection (HR) and RFA have been used increasingly in the treatment of colorectal liver metastases. Study A systemic review was performed to determine the impact of treatment modality of solitary liver metastasis on recurrence patterns, disease-free survival, and overall survival (OS) rates. Results Solitary liver metastases were treated by HR in 116 patients (75.8%) and 37 patients (24.2%) were treated with RFA. Prognostic factors, recurrence rate, recurrence patterns, and survival rates were analyzed. The cumulative 3-year and 5-year local recurrence free survival rates were markedly higher in the HR group (88.0% and 84.6%) as compared with those in the RFA group [53.3% and 42.6%, respectively (P≤0.001)]. The 5-year OS rate was lower in the RFA group as compared with the HR group without statistical significance (5-year OS, 65.7% in the HR, 48.5% in the RFA group, P=0.227). Conclusions Despite of higher local recurrence rate, RFA may be considered as a therapeutic option for patients who are considered unsuitable for conventional surgical treatment. Randomized prospective controlled trials comparing the therapeutic outcome of RFA and HR are definitely warranted.
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