珊瑚
立体化学
二萜
腔肠动物
化学
肿瘤细胞
萜类
内酯
生药学
二维核磁共振波谱
蛇床子属
生物
生物活性
生物化学
体外
生态学
癌症研究
作者
Guoqiang Li,Zhang Yan-ling,Zhiwei Deng,Leen van Ofwegen,Peter Proksch,Wenhan Lin
摘要
Five new alpha-methylene-gamma-lactone-bearing cembranoid diterpenes, sinularolides A-E (1-5), along with 10 known cembranoids, were isolated from the soft coral Sinularia gibberosa. Their structures were determined by extensive spectroscopic (IR, MS, 2D NMR) data analysis. Compounds 2-5 showed moderate activity against selected tumor cell lines.
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(2025-6-4)
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