化学
戒指(化学)
立体化学
环氧化物
真菌
脚手架
单胺氧化酶
二维核磁共振波谱
有机化学
酶
植物
催化作用
医学
生物
生物医学工程
作者
Hai-E. Ding,Zhiwei Yang,Sheng Li,Shuangyan Zhou,Shuo Li,Xiaojun Yao,Kang-Kang Zhi,Yonggang Wang,Fei Zhang
标识
DOI:10.1016/j.tetlet.2015.10.063
摘要
Secovironolide (1) was purified from the culture broth of Talaromyces wortmanni and is the first example of a furanosteroid scaffold bearing a five-membered B ring. The structure of 1 was elucidated by comprehensive NMR spectroscopy and single-crystal X-ray crystallography. Additional known viridian derivatives (2–5, 7) were isolated, including the new epoxide containing compound, epoxyvirone (6). Isolates were tested for monoamine oxidase (MAO) inhibitory activity and showed only weak activity.
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