疾病
生物
遗传分析
遗传学
医学
计算生物学
进化生物学
作者
William K. Scott,Margaret A. Pericak-Vance,Jonathan L. Haines
出处
期刊:Science
[American Association for the Advancement of Science (AAAS)]
日期:2006-05-05
被引量:166
摘要
Neil Risch, in a series of seminal papers in 1990 ([1][1], [2][2]), demonstrated the utility of sib-pair linkage analysis in identifying genes for complex genetic traits. In doing so, he defined what is the current paradigm for the genetic dissection of common complex genetic diseases. The recent
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