医学
疾病
青光眼
阿尔茨海默病
神经科学
黄斑变性
生物标志物
生物信息学
神经影像学
精密医学
神经退行性变
痴呆
作者
Alessio Martucci,Eliseo Picchi,Francesca Di Giuliano,Giulio Pocobelli,Raffaele Mancino,Nicola Toschi,Rossella Russo,Roberto Floris,Francesco Garaci,Carlo Nucci
标识
DOI:10.1016/j.coph.2021.12.003
摘要
Glaucoma is a leading cause of blindness worldwide. Although intraocular pressure is the main risk factor for glaucoma, several intraocular pressure independent factors have been associated with the risk of developing the disease and its progression. The diagnosis of glaucoma relies on clinical features of the optic nerve, visual field test, and optical coherence tomography. However, the multidisciplinary aspect of the disease suggests that other biomarkers may be useful for the diagnosis, thus underling the importance of novel imaging techniques supporting clinicians. This review analyzes the common pathogenic mechanisms between glaucoma and Alzheimer's disease and the possible novel approaches for diagnosis and follow up.
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