Sam’s Net: A Self-Augmented Multistage Deep-Learning Network for End-to-End Reconstruction of Limited Angle CT

稳健性(进化) 计算机科学 迭代重建 加权 人工智能 算法 缩小 深度学习 人工神经网络 数学优化 计算机视觉 数学 放射科 基因 医学 生物化学 化学 程序设计语言
作者
Changyu Chen,Yuxiang Xing,Hewei Gao,Li Zhang,Zhiqiang Chen
出处
期刊:IEEE Transactions on Medical Imaging [Institute of Electrical and Electronics Engineers]
卷期号:41 (10): 2912-2924 被引量:32
标识
DOI:10.1109/tmi.2022.3175529
摘要

Limited angle reconstruction is a typical ill-posed problem in computed tomography (CT). Given incomplete projection data, images reconstructed by conventional analytical algorithms and iterative methods suffer from severe structural distortions and artifacts. In this paper, we proposed a self-augmented multi-stage deep-learning network (Sam's Net) for end-to-end reconstruction of limited angle CT. With the merit of the alternating minimization technique, Sam's Net integrates multi-stage self-constraints into cross-domain optimization to provide additional constraints on the manifold of neural networks. In practice, a sinogram completion network (SCNet) and artifact suppression network (ASNet), together with domain transformation layers constitute the backbone for cross-domain optimization. An online self-augmentation module was designed following the manner defined by alternating minimization, which enables a self-augmented learning procedure and multi-stage inference manner. Besides, a substitution operation was applied as a hard constraint for the solution space based on the data fidelity and a learnable weighting layer was constructed for data consistency refinement. Sam's Net forms a new framework for ill-posed reconstruction problems. In the training phase, the self-augmented procedure guides the optimization into a tightened solution space with enriched diverse data distribution and enhanced data consistency. In the inference phase, multi-stage prediction can improve performance progressively. Extensive experiments with both simulated and practical projections under 90-degree and 120-degree fan-beam configurations validate that Sam's Net can significantly improve the reconstruction quality with high stability and robustness.
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