High performance electrochemical electrode based on polymeric composite film for sensing of dopamine and catechol

A highly conductive and electrochemically active film has been successfully fabricated by combining beta-cyclodextrin with acid-treated poly(3, 4-ethylenedioxythiophene):polystyrene (denoted as CD-f-PEDOT:PSS). The unique properties of the high performance CD-f-PEDOT: PSS sensor was investigated by utilizing X-ray photoelectron spectroscopy, atomic force microscope, cyclic voltammetry and amperometric i-t, etc. The CD-f-PEDOT:PSS film exhibits high-sensitivity towards dopamine (DA) and catechol (CT) without employing expensive noble metal or indium tin oxide (ITO) substrate and consuming much more time to polish the surface of traditional electrodes. The detection limits (S/N = 3) for DA and CT in phosphate buffer solutions (PBS, pH = 7.4) are 9.596 nM and 0.0275 μM, respectively. Furthermore, the CD-f-PEDOT: PSS film sensor exhibits good anti-interference and reproducibility. The encouraging results as well as facile preparation method suggest the CD-f-PEDOT: PSS film sensor is a promising alternative electrode to traditional ones such as ITO, gold or glassy carbon electrodes.