浆母细胞性淋巴瘤
淋巴瘤
流行病学
医学
疾病
人类免疫缺陷病毒(HIV)
病理
免疫学
作者
Supreet Kaur,Sudarsan Kollimuttathuillam
标识
DOI:10.1016/j.clml.2023.05.014
摘要
Plasmablastic Lymphoma is a rare large B-cell lymphoma with unique immunohistochemical and morphological features. It was most commonly associated with HIV infection; however, it's now seen in other immunosuppressed states like autoimmune conditions, post-transplant settings, and even in elderly immunocompetent individuals. Although rare, it is an aggressive lymphoma with unfavorable outcomes. The aim of this manuscript is to have an in-depth review of the current knowledge of epidemiology, pathophysiology, prognostic markers, and treatment approaches currently in use and in clinical trials for this challenging disease.
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