A redox-active iron complex as an immunogenic cell death-I inducer with NIR-II photoacoustic properties: a potential theragnostic agent for “cold tumors”

Fe( iii )-sirtinol nanoaggregates trigger immunogenic cell death-I and exhibit NIR-II photoacoustic properties, offering a dual-function approach to warm up “cold” tumors by combining immune activation with deep-tissue imaging capability.