PI3K/AKT/mTOR通路
结直肠癌
转移
癌症研究
选择性拼接
医学
RNA剪接
肿瘤科
癌症
细胞凋亡
生物
内科学
基因
遗传学
外显子
核糖核酸
作者
Tong Xu,Xichuan Li,Wennan Zhao,Xue Wang,Leixin Jin,Zhiqiang Feng,Huixiang Li,Mingzhe Zhang,Yiqing Tian,Ge Hu,Yue Yuan,Xintong Dai,Changliang Shan,Weihua Zhang,Chunze Zhang,Youcai Zhang
标识
DOI：10.1186/s13046-024-03053-4
摘要
Aberrant alternative splicing (AS) is a pervasive event during colorectal cancer (CRC) development. SF3B3 is a splicing factor component of U2 small nuclear ribonucleoproteins which are crucial for early stages of spliceosome assembly. The role of SF3B3 in CRC remains unknown.
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