Synthesis and Characterization of Heptakis-(2,3,6-O-allyl)-β-CD

Heptakis (2,3,6 O allyl) β CD have been synthesized by modification of β CD with ally bromide using NaOH as a catalyst. The influence of the reaction temperature and time, the amount of the catalyst and ally bromide on the synthesis was investigated. The optimum experimental conditions were established by the method of orthogonal experiment as follows: n(β CD)∶n(ally bromide)=1∶86.92, n(NaOH)∶n(ally bromide)=1∶1.052. The target compound was characterized by elemental analysis, IR, 1H NMR and FAB MS.