Expression and significance of estrogen receptor,progesterone receptor in non-small cell lung cancer

Objective To investigate the correspondence between the expression of estrogen receptor(ER),progesterone receptor(PR) in non-small lung cancer.Methods The immunohistochemical way S-P was employed to estimate the ER and PR in non-small lung cancer.Results The positive rates of ER and PR were 45.2% and 40.4%.The expression rates of ER and PR in adeno-carcinoma were apparently higher than that in other types of lung cancer tissues (P 0.01).In lung cancer the expressions of ER and PR were not related to the sex,age,clinical stage,degree of differentiation of tumor cells(P 0.05).There was no apparent difference in statistics of the non-tumor survival rate between the positive and negative ER and PR patients with in one,three postoperative years(P 0.05).Conclusion ER and PR are present in lung cancer,they can be an index as a steroid-aided therapy with a good prospect.