作者
Thomas Hugues,V. Lacroix-Hugues,Khelil Yaïci,P Gibelin,Inês Zimbarra Cabrita,S. Pires,Alexandra Nunes,Carla Sousa,Nuno Cortez‐Dias,Fausto J. Pinto,Anna Szymańska,Wojciech Braksator,Filip M. Szymański,Michael S. Chmielewski,Mirosław Dłużniewski,P. Alonso Fernandez,Ana Andrés Lahuerta,Vicente Miró Palau,Francisco Buendía Fuentes,B. Igual Munoz
摘要
Background: The range of excursions of the mitral or tricuspid annulus measured in mm by 2D or TM mode echocardiography has been shown to reflect the systolic function of both ventricles.We studied a new technique based on a tissue tracking algorithm that is ultrasound beam angle independent for automated detection of mitral annular displacement (MAD) (QLAB, Philips Medical Imaging).Aim: To validate the accuracy of MAD (mitral annular displacement) assessed as a surrogate for determination of the left ventricular function in comparaison with biplane LVEF and 3D LVEF Methode and patient: Digital cine loops of the apical four-and two-chamber views and 3D view were obtained in 204 consecutive patients (age 66+18.6 years, 56% male, heart rate 76+13.4,BMI 24.9+4.8 and biplane LVEF 55.7+13.6%)referred for transthoracic echocardiography (Philips iE33) at the Princesse Grace Hospital.Speckle tracking software (QLAb; Philips Medical System) was subsequently used to measure MAD offline.3 points were selected in each view as user-defined anatomic andmarks.The longitudinal displacement of both annular points and a calculated midpoint was tracked throughout the cardiac cycle in each view.mMAD = (4-ch MAD + 2-ch MAD)/2.Results: 4-chamber MAD was correlated with 4-chamber LVEF (R 2 =0,44; p,0,0001) and with Sa (R 2 =0,43; p, 0,0001).2-chamber MAD was correlated with 2-chamber LVEF (R 2 =0,37; p,0,0001).mMAD was correlated with biplane LVEF (R 2 = 0,47 p,0.0001) and 3D LVEF (R 2 = 0,48; p,0.0001).For patient with LVEF .50%, negative correlation was found between MAD and age (R 2 =0.25, p,0.0001).9mm predicted left ventricular dysfunction (biplane LVEF , 50%) with a sensitivity of 81,9% and a specificity of 88,9%.A value of MAD ≥12 mm predicted 2D LVEF .50% (negative predictive value of 97%).A value of MAD , 7mm predicted left ventricular dysfunction (biplane LVEF , 40%) with a sensitivity of 83,8% and a specificity of 91%.Conclusion: We found a significant correlation between both measures of systolic function MAD, biplane LVEF and 3D LVEF.As shown by De Cara (JASE 2005; 18: