C−H Activation Based Copper‐Catalyzed One‐Shot Synthesis of N,O‐Bidentate Organic Difluoroboron Complexes

Organic BF₂ complexes exhibit characteristics such as large Stokes shift, high quantum yield, strong emission intensity, and robust chemical stability, thereby being extensively used in various applications. Herein, we disclose a novel copper-catalyzed cascade C-H activation/acyloxylation and difluoroboronation of 2-phenylpyridine derivatives, thus providing a straightforward and rapid gateway to a series of N,O-bidentate organic BF₂ complexes with excellent photophysical properties. Mechanism studies demonstrate that AgBF₄ services as BF₂ source and oxidant for this elegant transformation. Most of these BF₂ complexes have broad and intense absorption and emission bands, and display bright and intensive blue fluorescence as well as large Stokes shifts.