Advances in Preparation of Cyclodextrin‐Based Stimulus‐Responsive Carriers and Their Applications in Delivery of Functional Spices

ABSTRACT Spices are substances that can be detected by the sense of smell or taste in their natural state. Currently, research on functional spices with properties such as anti‐tumour, vascularisation, anti‐inflammatory, and antibacterial effects attracts a lot of attention. However, comprehensive reviews on spices and their delivery systems remain limited. Among the various carriers used for spice delivery, cyclodextrins are widely applied due to their unique properties, which feature a hydrophobic interior and a hydrophilic exterior, particularly in the delivery of poorly soluble spices. In this study, representative functional spices and their mechanisms of action are introduced, then cyclodextrins and stimulus‐responsive cyclodextrin‐based delivery systems are summarised, and their applications in the field of spice delivery are discussed. Furthermore, the challenges faced in spice delivery and the future direction of cyclodextrin‐based carriers are proposed to promote the construction of an effective delivery system.