表观遗传学
化学
计算生物学
化学生物学
次生代谢
生物化学
生物
生物合成
基因
作者
Huawei Lv,Wenjing Li,Ping Xu,Jianguo Tang,Yu‐Guo Zheng,Yu Wan,Yanwei Lin,Hong Wang,Xing‐Nuo Li
标识
DOI:10.1016/j.bioorg.2023.107093
摘要
Fungi are microorganisms with biosynthetic potential that are capable of producing a wide range of chemically diverse and biologically interesting small molecules. Chemical epigenetic manipulation has been increasingly explored as a simple and powerful tool to induce the production of additional microbial secondary metabolites in fungi. This review focuses on chemical epigenetic manipulation in fungi and summarizes 379 epigenetic manipulation products discovered from 2008 to 2022 to promote the discovery of their medicinal value.
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