纳米光子学
生物分子
等离子体子
圆二色性
纳米技术
对映体
材料科学
化学
光电子学
立体化学
作者
Fei Wang,Xue Wang,Xinchao Lu,Chengjun Huang
出处
期刊:Biosensors
[MDPI AG]
日期:2024-01-12
卷期号:14 (1): 39-39
摘要
Chiral sensing is crucial in the fields of biology and the pharmaceutical industry. Many naturally occurring biomolecules, i.e., amino acids, sugars, and nucleotides, are inherently chiral. Their enantiomers are strongly associated with the pharmacological effects of chiral drugs. Owing to the extremely weak chiral light-matter interactions, chiral sensing at an optical frequency is challenging, especially when trace amounts of molecules are involved. The nanophotonic platform allows for a stronger interaction between the chiral molecules and light to enhance chiral sensing. Here, we review the recent progress in nanophotonic-enhanced chiral sensing, with a focus on the superchiral near-field and enhanced circular dichroism (CD) spectroscopy generated in both the dielectric and in plasmonic structures. In addition, the recent applications of chiral sensing in biomedical fields are discussed, including the detection and treatment of difficult diseases, i.e., Alzheimer's disease, diabetes, and cancer.
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