[Safety and effectiveness of interventional bronchoscopy under general anesthesia in the elderly patients with central airway stenosis: a retrospective study].

We retrospectively reviewed the clinical data of patients aged 65 years and older with central airway stenosis who underwent therapeutic bronchoscopy under general anesthesia in Beijing Tiantan Hospital from January 2012 to September 2022. A total of 167 patients were included in the study. One or more comorbidities were present in 151 patients. The number of operation procedure was 230 times. Laryngeal mask ventilation under general anesthesia and electrotomy was the most common method of airway management and operation. The incidence of major complications was 5.2%. One patient with granular cell tumor died of major bleeding during stent removal. The primary malignant lesion, number of comorbidities, electrolyte disturbances and rigid bronchoscopy were risk factors for major complications, and the difference was statistically significant. The overall response rate was 99.4%. The airway stenosis grade, dyspnea score and KPS value were improved, and the differences were statistically significant. Interventional bronchoscopy under general anesthesia appeared to be safe and effective in patients aged 65 years and older with central airway stenosis. Age should not be a contraindication to interventional bronchoscopy.回顾性分析2012年1月至2022年9月在我科行全身麻醉下介入治疗的167例年龄≥65岁老年中央气道狭窄患者的临床资料。151例患者至少有一种合并症。共治疗230次。全身麻醉下喉罩通气和电刀是最常见的通气和治疗方式。严重并发症的发生率为5.2%。其中1例颗粒细胞瘤患者行支架取出过程中因大出血死亡。原发恶性病变、合并症数量、电解质紊乱和硬质支气管镜是严重并发症的危险因素，差异有统计学意义。治疗有效率为99.4%。气道狭窄程度分级、气促评分和KPS均较治疗前改善，差异有统计学意义（P<0.05）。本研究显示，老年中央气道狭窄患者在全身麻醉下行支气管镜介入治疗具有良好的安全性和有效性，年龄不应再成为手术禁忌证。.