过敏性支气管肺曲菌病
指南
医学
肺活量测定
哮喘
内科学
曲菌病
重症监护医学
免疫球蛋白E
免疫学
病理
抗体
作者
Inderpaul Singh Sehgal,Valliappan Muthu,Danila Seidel,Rosanne Sprute,Darius Armstrong‐James,Koichiro Asano,James D. Chalmers,Jean‐Pierre Gangneux,Cendrine Godet,Helmut J.F. Salzer,Oliver A. Cornely,Ritesh Agarwal
出处
期刊:Mycoses
[Wiley]
日期:2024-10-01
卷期号:67 (10)
被引量:1
摘要
ABSTRACT Objectives Allergic bronchopulmonary aspergillosis (ABPA) is a complex lung disease associated with significant morbidity. The ABPA Working Group (AWG) of the International Society for Human and Animal Mycology (ISHAM) revised their management guidelines in 2024, but there is currently no standardised tool to assess adherence to these recommendations. Methods We extracted key recommendations from the updated 2024 ISHAM‐AWG guidelines, focusing on critical areas: screening and diagnosis of ABPA, managing acute and treatment‐dependent ABPA, and monitoring treatment response. Each item was assigned a score ranging from zero to three. We assigned negative scores to interventions not recommended by the guidelines. Results We identified 38 items indicative of optimal clinical care for patients with ABPA. The score for screening asthmatics for ABPA was set at three points. For diagnosing ABPA, 16 items were included, with a score ranging from 12 to 16 points, depending on the specific components used (predisposing conditions, serum A . fumigatus ‐specific IgE and IgG, serum total IgE, blood eosinophil count and chest computed tomography). The management of acute ABPA comprised 11 items, with a maximum score of three points. For treatment‐dependent ABPA, there were nine items (scores ranging from −3 to 6). Follow‐up care comprised 10 items with a maximum score of 10–13 points, covering imaging, spirometry, testing serum total IgE levels and therapeutic drug monitoring. Conclusions The EQUAL ABPA score has been developed as a comprehensive tool to quantify guideline adherence. Future studies will evaluate to which extent guideline adherence is associated with improved clinical outcomes for patients with ABPA.
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