The effects of ciclosporin and methotrexate on kidney function in the treatment of severe atopic dermatitis in children – results from the TREAT trial

Ciclosporin (CyA) and methotrexate (MTX) are frequently prescribed drugs for the treatment of atopic dermatitis in children and young people. Both can affect renal function and frequent blood monitoring is standard to monitor safety. We show that both CyA and MTX are not associated with decreased renal function and are safe and effective as a treatment for atopic dermatitis in children and young people.