白藜芦醇
化学
计算生物学
组合化学
药理学
立体化学
生物化学
生物
作者
Borislav Kovačević,Ivana Šagud,Katarina Marija Drmić,Milena Mlakić,Irena Škorić,Sandra Babić
出处
期刊:Molecules
[Multidisciplinary Digital Publishing Institute]
日期:2024-11-20
卷期号:29 (22): 5481-5481
标识
DOI:10.3390/molecules29225481
摘要
Acetylcholinesterase and butyrylcholinesterase are two related enzymes that represent pharmacologically suitable targets in neurodegenerative disorders, given their physiological roles in the body. The treatment of neurodegenerative disorders currently includes common reversible cholinesterase inhibitors. Resveratrol analogues, as the molecules in focus, have shown the very strong inhibition potential of cholinesterases. In this research, experimental and DFT approaches for their p
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