亲爱的研友该休息了!由于当前在线用户较少,发布求助请尽量完整的填写文献信息,科研通机器人24小时在线,伴您度过漫漫科研夜!身体可是革命的本钱,早点休息,好梦!

Angiography‐derived functional assessment of left main coronary stenoses

医学 冠状动脉造影 血管造影 心脏病学 内科学 放射科 心肌梗塞
作者
Sonoka Yuasa,Francesco Lauri,Hernán Mejía‐Rentería,Catherine Liontou,Hyun-Jong Lee,Toru Tanigaki,Masafumi Nakayama,Takayuki Warisawa,Takashi Uchiyama,Hitoshi Matsuo,Justin E. Davies,Takao Sato,Javier Escaned
出处
期刊:Catheterization and Cardiovascular Interventions [Wiley]
卷期号:101 (6): 1045-1052 被引量:2
标识
DOI:10.1002/ccd.30633
摘要

Abstract Objectives We aimed to evaluate the diagnostic accuracy of quantitative flow ratio (QFR) in left main (LM) coronary stenoses, using Fractional Flow Reserve (FFR) as reference. Background QFR has demonstrated a high accuracy in determining the functional relevance of coronary stenoses in non‐LM. However, there is an important paucity of data regarding its diagnostic value in the specific anatomical subset of LM disease. Methods This is a retrospective, observational, multicenter, international, and blinded study including patients with LM stenoses. Cases with significant ostial LM disease were excluded. QFR was calculated from conventional angiograms at blinded fashion with respect to FFR. Results Sixty‐seven patients with LM stenoses were analyzed. Overall, LM had intermediate severity, both from angiographic (diameter stenosis [%DS] 43.8 ± 11.1%) and functional perspective (FFR 0.756 ± 0.105). Mean QFR was 0.733 ± 0.159. Correlation between QFR and FFR was moderate ( r = 0.590). Positive and negative predictive value, sensitivity and specificity were 85.4%, 64%, 85.4%, and 69.6% respectively. Classification agreement of QFR and FFR in terms of functional stenosis severity was 78.1%. Area under the receiver operating characteristics of QFR using FFR as reference was 0.82 [95% confidence interval [CI], 0.71−0.93], and significantly better than angiographic evaluation including %DS (area under the receiver‐operating characteristic curve [AUC] 0.45 [95% CI, 0.32−0.58], p < 0.001) and minimum lumen diameter (AUC 0.60 [95% CI, 0.47−0.74], p < 0.001). Conclusions Compared with FFR, QFR has acceptable diagnostic performance in determining the functional relevance of LM stenosis, being better than conventional angiographic assessment. Nonetheless, caution should be taken when applying functional angiography techniques for the assessment of LM stenosis given its particular anatomical characteristics.

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
3秒前
吱吱草莓派完成签到 ,获得积分10
6秒前
赘婿应助zekunshen采纳,获得30
24秒前
39秒前
zekunshen发布了新的文献求助30
42秒前
完美世界应助科研通管家采纳,获得10
46秒前
zekunshen完成签到,获得积分10
56秒前
思源应助JazzWon采纳,获得10
1分钟前
1分钟前
1分钟前
我的小名叫雷锋完成签到 ,获得积分10
2分钟前
2分钟前
HGalong应助科研通管家采纳,获得10
2分钟前
2分钟前
丘比特应助ygl0217采纳,获得10
3分钟前
张之昂完成签到 ,获得积分10
3分钟前
3分钟前
3分钟前
3分钟前
秋雪瑶应助Zhou采纳,获得30
3分钟前
无花果应助缓慢的念之采纳,获得10
3分钟前
张XX完成签到 ,获得积分10
3分钟前
4分钟前
tszjw168完成签到 ,获得积分10
4分钟前
4分钟前
ygl0217发布了新的文献求助10
4分钟前
4分钟前
4分钟前
代扁扁完成签到 ,获得积分10
5分钟前
Yaon-Xu完成签到,获得积分10
5分钟前
跳跃笑晴完成签到 ,获得积分10
5分钟前
xinran关注了科研通微信公众号
6分钟前
风雪丽人完成签到,获得积分10
6分钟前
6分钟前
xinran发布了新的文献求助30
6分钟前
杨二锤完成签到 ,获得积分10
6分钟前
laihuimin完成签到,获得积分10
6分钟前
7分钟前
Zhou发布了新的文献求助30
7分钟前
tuanheqi完成签到,获得积分0
7分钟前
高分求助中
Manual of Clinical Microbiology, 4 Volume Set (ASM Books) 13th Edition 1000
Sport in der Antike 800
De arte gymnastica. The art of gymnastics 600
Berns Ziesemer - Maos deutscher Topagent: Wie China die Bundesrepublik eroberte 500
Stephen R. Mackinnon - Chen Hansheng: China’s Last Romantic Revolutionary (2023) 500
Sport in der Antike Hardcover – March 1, 2015 500
Psychological Warfare Operations at Lower Echelons in the Eighth Army, July 1952 – July 1953 400
热门求助领域 (近24小时)
化学 材料科学 医学 生物 有机化学 工程类 生物化学 纳米技术 物理 内科学 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 电极 光电子学 量子力学
热门帖子
关注 科研通微信公众号,转发送积分 2424706
求助须知:如何正确求助?哪些是违规求助? 2112393
关于积分的说明 5350390
捐赠科研通 1839964
什么是DOI,文献DOI怎么找? 915890
版权声明 561327
科研通“疑难数据库(出版商)”最低求助积分说明 489899