Dual-Functional Nanotherapy-Reinforced Hydrogel for Synergistic Antimicrobial and Immunomodulatory Oral Tissue Repair

evaluations across skin wound, oral ulcer, and periodontitis models demonstrate prolonged microbial defense, significant inflammation resolution, and accelerated tissue regeneration. This nanotherapy-mediated multi-interaction reinforcement strategy can serve as a versatile approach for engineering self-adaptive hydrogels to address complex challenges in oral regenerative medicine.