Optimizing Xenon 129 Ventilation MRI in Cystic Fibrosis with Spiral Imaging and Flip-Angle Correction

Faster and more accurate xenon 129 ventilation MRI was achieved in individuals with cystic fibrosis by combining two-dimensional spiral acquisition, keyhole-based flip-angle correction, and median-anchored generalized linear binning calibrated to normative data from healthy controls.