Surface modification of PDMS by gradient-induced migration of embedded Pluronic

We present a simple, flexible, and environmentally friendly approach to modify the PDMS surface by gradient-induced migration of embedded amphiphilic copolymer Pluronic F127 and the hydrophobic interaction between the migrated embedded Pluronic and substrate molecules near the surface. The modified surface is hydrophilic and reduces the nonspecific adsorption of protein significantly.