A Randomized Controlled Trial of Mobile Health Intervention in Patients With Heart Failure and Diabetes

健康 医学 随机对照试验 生活质量(医疗保健) 糖尿病 临床终点 物理疗法 干预(咨询) 心理干预 内科学 护理部 内分泌学
作者
G. Michael Felker,Abhinav Sharma,Robert J. Mentz,Lilin She,Cynthia L. Green,Bradi B. Granger,John F. Heitner,Lauren B. Cooper,J. Teuteberg,Justin L. Grodin,Kenneth Rosenfield,Lori L. Hudson,Lydia Coulter Kwee,Olga Ilkayeva,Svati H. Shah
出处
期刊:Journal of Cardiac Failure [Elsevier BV]
卷期号:28 (11): 1575-1583 被引量:13
标识
DOI:10.1016/j.cardfail.2022.07.048
摘要

Mobile health (mHealth) platforms can affect health behaviors but have not been rigorously tested in randomized trials.We sought to evaluate the effectiveness of a pragmatic mHealth intervention in patients with heart failure (HF) and diabetes (DM).We conducted a multicenter randomized trial in 187 patients with both HF and DM to assess an mHealth intervention to improve physical activity and medication adherence compared to usual care. The primary endpoint was change in mean daily step count from baseline through 3 months. Other outcomes included medication adherence, health-related quality of life and metabolomic profiling.The mHealth group had an increase in daily step count of 151 steps/day at 3 months, whereas the usual-care group had a decline of 162 steps/day (least squares mean between-group difference = 313 steps/day; 95% CI: 8 619; P = 0.044). Medication adherence, measured using the Voils Adherence Questionnaire, did not change from baseline to 3 months (LS-mean change -0.08 in mHealth vs -0.15 in usual care; P = 0.47). The mHealth group had an improvement in Kansas City Cardiomyopathy Questionnaire Overall Summary Score compared to the usual-care group (LS-mean difference = 5.5 points, 95% CI: 1.4, 9.6; P = 0.009). Thirteen metabolites, primarily medium- and long-chain acylcarnitines, changed differently between treatment groups from baseline to 3 months (P < 0.05).In patients with HF and DM, a 3-month mHealth intervention significantly improved daily physical activity, health-related quality of life and metabolomic markers of cardiovascular health but not medication adherence.Heart failure (HF) and diabetes (DM) have overlapping biological and behavioral risk factors. We conducted a multicenter randomized, clinical trial in 187 patients with both HF (regardless of ejection fraction) and DM to assess whether an mHealth intervention could improve physical activity and medication adherence. The mHealth group had an increase in mean daily step count and quality of life but not in medication adherence. Medium- and long-chain acylcarnitines changed differently in treatment groups from baseline to 3 months (P < 0.05). These data have important implications for designing effective lifestyle interventions in HF and DM.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
刚刚
tenfarmers完成签到,获得积分10
3秒前
火星上冥茗完成签到 ,获得积分10
4秒前
吃点水果保护局完成签到 ,获得积分10
4秒前
研友_Z1eDgZ发布了新的文献求助10
4秒前
chen发布了新的文献求助10
4秒前
5秒前
Lily完成签到,获得积分10
5秒前
科研通AI2S应助Nancy采纳,获得10
6秒前
啦啦啦发布了新的文献求助10
7秒前
科研通AI5应助李苗苗采纳,获得10
9秒前
小小苏荷发布了新的文献求助10
9秒前
Howard完成签到,获得积分10
12秒前
13秒前
111完成签到,获得积分10
13秒前
wenbo完成签到,获得积分10
16秒前
简单的千凝应助shelemi采纳,获得50
19秒前
LaTeXer应助shelemi采纳,获得50
19秒前
简单的千凝应助shelemi采纳,获得50
19秒前
19秒前
iNk应助shelemi采纳,获得10
19秒前
怕孤独的飞飞完成签到,获得积分10
19秒前
聪仔发布了新的文献求助10
20秒前
20秒前
20秒前
GAW完成签到,获得积分10
22秒前
李苗苗发布了新的文献求助10
24秒前
今后应助傲娇以晴采纳,获得30
24秒前
carbonhan发布了新的文献求助10
24秒前
北极光发布了新的文献求助10
25秒前
胜天半子完成签到 ,获得积分10
27秒前
123应助舒心的期待采纳,获得20
29秒前
30秒前
30秒前
麻辣小龙虾完成签到,获得积分10
32秒前
脑洞疼应助我要发sci采纳,获得10
32秒前
33秒前
33秒前
酷波er应助仿生人采纳,获得10
34秒前
JJ完成签到,获得积分10
34秒前
高分求助中
Les Mantodea de Guyane Insecta, Polyneoptera 2500
Technologies supporting mass customization of apparel: A pilot project 600
Introduction to Strong Mixing Conditions Volumes 1-3 500
China—Art—Modernity: A Critical Introduction to Chinese Visual Expression from the Beginning of the Twentieth Century to the Present Day 430
Tip60 complex regulates eggshell formation and oviposition in the white-backed planthopper, providing effective targets for pest control 400
A Field Guide to the Amphibians and Reptiles of Madagascar - Frank Glaw and Miguel Vences - 3rd Edition 400
China Gadabouts: New Frontiers of Humanitarian Nursing, 1941–51 400
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 物理 生物化学 纳米技术 计算机科学 化学工程 内科学 复合材料 物理化学 电极 遗传学 量子力学 基因 冶金 催化作用
热门帖子
关注 科研通微信公众号,转发送积分 3796439
求助须知:如何正确求助?哪些是违规求助? 3341670
关于积分的说明 10307098
捐赠科研通 3058243
什么是DOI,文献DOI怎么找? 1678070
邀请新用户注册赠送积分活动 805843
科研通“疑难数据库(出版商)”最低求助积分说明 762815