石墨烯
生物界面
氧化物
解吸
纳米技术
堆积
吸附
材料科学
化学
有机化学
冶金
作者
Biwu Liu,Shehan Salgado,Vivek Maheshwari,Juewen Liu
标识
DOI:10.1016/j.cocis.2016.09.001
摘要
Interfacing DNA oligonucleotides with graphene-based materials, especially graphene oxide, has produced many new sensors and devices. Since graphene oxide is an excellent fluorescence quencher, fluorescently labeled DNAs (probes) are nearly fully quenched upon adsorption. Addition of the complementary DNA results in probe desorption and fluorescence enhancement. Aside from its analytical applications, this system provides a fascinating topic for biointerface science. DNA can be adsorbed by graphene oxide via π–π stacking and hydrogen bonding, while it must overcome electrostatic repulsion at the same time. The mechanism of DNA-induced probe desorption has also been a topic of extensive discussion. In this article, DNA adsorption and desorption reactions and interactions with graphene oxide and related materials (e.g. graphene) are reviewed based on the current understandings. A few representative applications based on these processes are also described briefly.
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